Pergolide (Permax®)
This is an ergot derivative and, like bromocriptine, is indicated as adjunctive treatment with carbidopa/levodopa. In comparison to bromocriptine, it has a longer duration of action.
This drug has not been frequently studied in the treatment of early PD.
Side effects
- Diarrhea
- Nausea
- Constipation
- Indigestion
- Insomnia
- Motor disturbances
- Hallucinations
- Somnolence